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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6eef78a522bd9fd7c41123a5ee30f1dee2da4cf25c0bb05125e8c0acaa790c45' 
  AND token = '4fZZIpuNJ4eyl/2j7r+oYgzYQsTVCC3NTtNXJcAFW2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}