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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f43198f58a0f1110ad8e6265040a6ed30194b2209efeea0b04fca4fa5f6eb2d4' 
  AND token = '6hhhJx0H+G9/ObK2uCIlLF/d701YsdREQsQ/rgpe+lI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}