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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25baf11aad43ab074e11a45cdeedee2bdea8db9a627c119f17f3a5ffc649ac5d' 
  AND token = 'QmP6w7vxK2CVX2VVmrC/0CIFsr54H7d8pN7rfCzC2Fw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}