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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb54354389b21fc238fd4f52e44bae6dc33d27e94274f0d754bacbf85eebc045' 
  AND token = '78moctvrNWRYDJ4oW67R8AGu8rM29WoGkseIRBgeFk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}