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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f41be10254a35db4bc60165c1ee7fcfe6548aa0a0bbdb6b8117096333d1ce10' 
  AND token = 'FEtHQ6O8BYBWPwATecFP0+bxz6XAqDwjH+evnZbHp3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}