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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a861625ffffec6d546ede5ba83ae610571d55b3a9cbc0f87b0c7a78fe236bab' 
  AND token = 'OKE0D8wdkKLb0rmBuJ2KZyblTSJq8NRHy4AIwOPyTr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}