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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b3351ec24c151d15b58d9ea8a0f45e562ee323a17668467616296a42d769ee' 
  AND token = '/j0TZTKY7zvhrRBPmSDy7yV25rl/DR8F3uaM4paqAGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}