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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82d325925a62e687e92db1745e3662c9c0c0e9d87701b649819b62de383d016f' 
  AND token = 'nxhfEINKt3p2ICD8cImD+ziPq1luJVXVhGDa6Wy58zU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}