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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7f097a54bda6ff1a1d8d02ef5186ecf9158b68cc1ff1cc99f1d621a5214e432' 
  AND token = 'hx4yw1VcJ0DrNKBe5FpKl6ysucjAJIriALjYMYhaYpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}