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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2217d110179311735791f37665c6a0c0f5d6fd5ca6502e27ede84387246f2a91' 
  AND token = 'CMcDwu9cQ0vhyhMVc8VM1u4Qo8DsrLXfIT8BCfp/wjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}