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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50dc56a2167be9493449ccc456a01a2b46b4d920f43050aaf7aeac0418edce5a' 
  AND token = 'H8o+JsrUUbYUkOPp+4+6TzYdt6kJ/6Ec0CA4rn+6huk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}