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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a773aceae6fda7c3e8216d575b216e16ad619ce7b2c65a9126ab14f715eb24' 
  AND token = 'UJ4SDdd73QpNDw81MEtjVToxVlSTzeo19beIf2w9xIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}