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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8129e916438c0309df21ae86613419846f8cbf0e09ccc9de2286a067cf20b3bb' 
  AND token = 'm6bZNi+WeauaM74uFh6y4x/5g/DCV49EKJOR5kC7UpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}