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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8cc2d05f7299298d29f9e3116410a80710652b9112cf101a2257375f171d178' 
  AND token = 'Ouiqr4Bs8/Wn5lc/T8Edj5iBidjB0KTNba6iVyjT1Xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}