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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5b03ce31537a2b981cb3b95852e8949b484b21c85d8f24ec652bde12ed5f796' 
  AND token = 'fmq40xR6N2+ZJGUe4IERXn41c2YubxN6/3bI9qxb+ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}