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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73b8cc18baf841ad77f530232caf3b364068839425274e9a381c333075b91410' 
  AND token = 'eYopLv6+xVDCzSODsi9Oq7VWMbGuD04UmvXlyrC2Cn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}