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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '296b045393f9c1eb4038c66a614412e9074d4a9a8c93cab8a272effeb3c27e03' 
  AND token = '6KxGL+It1kfxAOiHybwcs3svk5uPqHdUTKXeId9OzUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}