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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '190a961a770a08a7481caeb6dcd6b8b29bcfd1e97aec5b3312e4e44d921ca07d' 
  AND token = 'y9Vlct4XOUgYEpxcMMTtnDTgq3MVy1NxRaiFuUxrt4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}