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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47ac538f0c4316d3bbd7e95550fa2133a644377a12edd0d5c1584d1ba1a933ac' 
  AND token = 'ltMHs1OYoSX2Pq4YYIN+htO6OvOzH7NwX2TcHfa3xV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}