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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7716e6748783c2cd6776a819924711a268f9f9f0440f65689ed4efe83f4edb05' 
  AND token = '2DA46oBGJkMi/k2zSLZlpzryVvA3fWHl0lXfg41R8Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}