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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26b1586f41413a737eab6d9a3fa005282b11d385ad40d1024076d9f39f594c05' 
  AND token = 'Kf1EVU3xHFwKAMpT5eXg2EAuSKrMnIXvRUp/Q8keTlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}