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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a377b5f8a06f293bf072ef7f9b321f6b6c79f37239058f4e5599a0d288a18407' 
  AND token = '61pw6xWLQ84rf76LZtGFp7rKf4yeukII7CYMBg7+pAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}