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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46d2dcb45450b63d4da018032846a83a689a6bd2cb6d9986c6bf0d8d9386e723' 
  AND token = 'XF654ForsFLFMfKDYH0SgS9aLRzrZpNpLNXqGbmO5DE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}