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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b740faf71cc830cc08dc93f55bdb8eb59be827b1057a58f772ea58e528e57ef2' 
  AND token = 'RwdMMETK80DRqvTbrVxqx1vXbqfitmeg4a0E53KzpNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}