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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8863392ca53f1e1235d591e7df5c6b23cf8e4b2915df9535ab68d1d54feb4184' 
  AND token = '7+Dlz2aYsWylINvl8Hzh2a6uzGM+3AKkJHCtN5gn0NE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}