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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c0e798e74aee9ae9e705f4e0eb16c83deee5d0c0c3286f768aaa17d22cff858' 
  AND token = 'bu4so6P3oJJV0VcqrNejCtVYh2DJ4NTfK8sPYuQSgbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}