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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e80f6ac84afc5d7093c5dd9429e377e51aa1a501942cca818bd4cee5d81a4732' 
  AND token = 'X/Vcg/E3xTLz6N8aeNPZYW995nihtgXwwEOBtQYH/fI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}