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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b867c38a4be4f671c54998d85dc49bb5bd3b548f74fdc6e020a47beec8196616' 
  AND token = 'lqgtjJmrMOeQGc5hsk09u+eTTxKYTS6gk5qwbP5hmK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}