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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dd773b7f1e1940605a4a4bdec46069426a0b0fd008767c1345a9651fa2c2ff2' 
  AND token = 'j/9NRoLrYCc9u9l5F+XA6d0aonK8nyaMI21zN7bKS04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}