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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3c00b7173cf283a7aa4be497c49ee76839b505d03d42ab2aa062f7257fcc908' 
  AND token = 'yYWe66gz0GxaqBnbMPD1nQ8lznBU0jXh/BwEOeMbk3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}