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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f3335ce8233be28093d4737321f4ed8be967aa7a40620ff6896ff5378ce621e' 
  AND token = 'Ee4SJ4jiyVX0YLDL9GH6iqes2GW/6xq463oalNOM1DE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}