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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32cfccb7a5a03d4161da6bd0e99d01292be755bc29aadb04c23fa1cf46d4529e' 
  AND token = 'MEwx7nDts8NCLnnl8Y+pGmKgUorEVKWXx0L/f1SIQw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}