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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd541d6e9732e0b314e65f2ba2c8141a2e6140bd48b66e90d53716d7eb31dc04d' 
  AND token = 'e1Y3JKhlufM1qFlJuVD2UrwrJdxrbS6D1iDusxMtU3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}