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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68e8d545f293deeb2cad3b06c635625dbccb9523e536572cb7d36d8e81281c2c' 
  AND token = 'UxDX+NoIU9Egzlw9najxCA9cX0kTwJ+e8P/VILUfzBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}