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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d2e66aa2a99393af8cff21ce5b96650a31c4db6b49606f19b28a2eea722351f' 
  AND token = 'BZ1xVuHZQLeVtkmAA3YZnevsopUESCX8r9qnfRUb9YQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}