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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e5810c48453f7279b64bc7110035e5025c40719e8334d9b8661c2e710019a0d' 
  AND token = 'uzt9Rt09qVsVhyc6glpenpiX4bh5VPtRl1B2QtCDToE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}