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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1d5ad82db90c22513bec7b168de4de883d273e2d2903e10f08e89fe768723be' 
  AND token = 'dXBEk3gkupOzxxi/R+DM43zxm5i1n3A1p5cRE8vMWf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}