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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3e42c44e29e2791e38a5de36cd5c780d55bddaff442a6a637d6d14071676e9a' 
  AND token = 'rSJ0hgfplVBYALU6MAxC32Q4HrSakRUjRNdanMIaHxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}