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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1afd42bb18033e373a88e90aabbf4045913aef4b812302ff5b2ce56c6c529c6f' 
  AND token = '5PsMRq4O9oiJqhLrml3NynIxHI9XY32jW1fKQVNcjIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}