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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a64d3b17fa79358f2258c7c15190a4af9a0c059ea3535aa2f72a9507505d8770' 
  AND token = 'ZAjc4i07nZJVByhXqtxMJp9c7gTxuTC2iY50vrxCpc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}