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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2374456d5614321165905bf63590edc22df1e07fd10a652a9ef2d9f1b6ec1132' 
  AND token = 'qUeE71G0njsXM6pvZjhC7RU41/0xcEGw13zfNGrpSdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}