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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2880dddfef7b9fcece7e3efa01eba1d99b25194cba932a5337b86b4759037a00' 
  AND token = 'HTRvv5ngjOV6Vli3I1mo0yfgUYtlnGUWjmIKGN8kDXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}