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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b401daa321ca6c2b77be535dc9d8d16fbfa37c90ebac921fe3dc6ea31444de' 
  AND token = 'v7Q/cIBlNrW7NFDk5D+EUevzCTFTjIlgA1rjylSMAkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}