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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57cf912da10fce8129870bc3e477f4c2c5c2b76171c2b26fd67a76fb9948ac09' 
  AND token = 'eJ1UOqwkDHPnSyOYMyq1RtUvq952qmo7jmTC6Ghkwp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}