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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06b342c8f3eedcce959514204ae1899937be435955e9bb09459c984f508edf69' 
  AND token = 'oIg6QYGzX2HAa1aNzUnaI3jlf8HjTD3SY1IfVxZT2Ts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}