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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '753a1df1d690ba6b8d3fb3607fe23e004f0c1032ceec3e609dbfeb0f4d22048c' 
  AND token = 'zy6iykAtPK8ysppcy2XDdQ8YI+Kv/yB3aShH6RQP4vM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}