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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86a6a862f084607dd5a06efe656ffab3563869f6d8baf402b04e842e4c3c5253' 
  AND token = 'CPZD99iIG6AEKvoFEPDM3b+uwVbqDdDZHiROvewRKgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}