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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cb898d357713dc7b7464f91c616655d3cd15435e6dfb775a5e81b94aa6a54eb' 
  AND token = 'SX10Bo1DmPZ1HhWGgfs259ZxHUSGf6VyGenHQx4bopQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}