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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c993f130e211bd9c7f7c49890bbc80ef6e8932501dad933f871662e89acf55b' 
  AND token = 'M5hbaCkzsKFtu+TO44PPdbQO+bImkTECzY2HDkWMhY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}