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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73e5c3c653e53b0ae241a0f2923f0a0b67724c41422e37035bb1ffa44ddef9bb' 
  AND token = 'VYStzg/0pGx+Bo1rVxMJ18QbvsMvGM2wnm+04h1T32I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}